Original Article
Volume: 2 | Issue: 2 | Published: Jan 14, 2020 | Pages: 99 - 106 | DOI: 10.24911/JBCGenetics/183-1574152719
Attitudes to prenatal diagnosis and termination of pregnancy for fetal abnormalities in Saudi couples: a single center experience
Authors: Maha Alshalan , Majid Alfadhel
Article Info
Authors
Maha Alshalan
Division of Genetics, Department of Pediatrics, King Abdullah specialized Childrens Hospital, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs (MNGHA), Riyadh, Saudi Arabia
Majid Alfadhel
Division of Genetics, Department of Pediatrics, King Abdullah specialized Childrens Hospital, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs (MNGHA), Riyadh, Saudi Arabia, Medical Genomics Research Department, King Abdullah International Medical Research Center (KAIMRC), Ministry of National Guard-Health Affairs (MNGHA), Riyadh, Saudi Arabia, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs (MNGHA), Riyadh, Saudi Arabia
Publication History
Received: November 19, 2019
Revised: December 24, 2019
Accepted: December 26, 2019
Published: January 14, 2020
Abstract
Background: Prenatal diagnosis (PND) is an effective method for early detection of genetics and hereditary diseases during pregnancy in order to help the couple to take the proper decision regarding affected fetus. The current study aimed at assessing the attitude of Saudi couple regarding prenatal diagnosis and termination of pregnancy (TOP) for fetal abnormalities. Methodology: A descriptive cross-sectional was carried out; 100 couples attended Genetic Clinics in King Abdullah Specialized Childrens Hospital in Riyadh, who were interviewed using an questionnaire consisting of four parts covering socio-demographic data of participants, family & obstetric history, knowledge, and attitude of couples regarding PND and TOP. Descriptive statistics and chi-square tests were used for data analysis. Results: The results of the study showed that the mean age of fathers were 38.8± 8.1 years, while the mean age of mothers were 33.9 ± 6.9 and most of the couples (93%) lived in the urban area. Among them, 47% of couples had a positive family history of genetic diseases; 16% of mothers performed PND in their previous pregnancies. Among them, 62% and 76% of fathers and mothers, respectively, had satisfactory knowledge about PND and TOP with a statistically significant difference between them. Conclusion: A comprehensive genetic counselling service offered to the couples may influence the decision on TOP. The awareness about PND and TOP is crucial to obtain good understanding and positive future strategies.
Keywords: Prenatal diagnosis, termination of pregnancy, fetal abnormalities, Saudi couples, attitude
